ATPase Class V Type 10D (ATP10D)

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ATPVD; P4-ATPase flippase complex alpha subunit ATP10D; Probable phospholipid-transporting ATPase VD

ATPase Class V Type 10D (ATP10D)
The P-type ATPases comprise a well-studied family of proteins involved in the active transport of charged substrates across biological membranes. Atp10d, as well as its human counterpart. The presence of P-type ATPase consensus motifs and phylogenetic analysis showed that this gene is a member of the type IV, putative amphipath transporters subfamily. Atp10d is expressed in kidney and placenta. C57BL/6 strain carries a constitutive stop codon in the sequence of Atp10d exon 12, whereas 14 other inbred mouse strains show an uninterrupted reading frame at this location. This mutation in C57BL/6 should lead to a non-functional protein, suggesting that this gene may not be essential. Atp10d in the fat-prone phenotype of the C57BL/6 strain and its physical mapping within a QTL associated with HDL-cholesterol levels.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase Class V Type 10D (ATP10D) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase Class V Type 10D (ATP10D) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase Class V Type 10D (ATP10D) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase Class V Type 10D (ATP10D) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase Class V Type 10D (ATP10D) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase Class V Type 10D (ATP10D) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase Class V Type 10D (ATP10D) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase Class V Type 10D (ATP10D) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase Class V Type 10D (ATP10D) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase Class V Type 10D (ATP10D) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase Class V Type 10D (ATP10D) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase Class V Type 10D (ATP10D) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase Class V Type 10D (ATP10D) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase Class V Type 10D (ATP10D) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase Class V Type 10D (ATP10D) ELISA Kit Customized Service Offer
  1. "Characterization of a putative type IV aminophospholipid transporter P-type ATPase."Mamm. Genome 14:21-30(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:143-150(2000) [PubMed] [Europe PMC] [Abstract]
  6. "ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner."J. Biol. Chem. 286:38159-38167(2011) [PubMed] [Europe PMC] [Abstract]