Aldo Keto Reductase Family 1, Member B15 (AKR1B15)

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Estradiol 17-beta-dehydrogenase AKR1B15

Aldo Keto Reductase Family 1, Member B15 (AKR1B15)
AKR1B15, Belongs to the aldo/keto reductase family.Found in many tissues. Highly expressed in small intestine, colon and adrenal gland. Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
The aldo-keto reductase family is a family of enzymes that includes a number of related monomeric NADPH-dependent oxidoreductases, such as aldehyde reductase, aldose reductase, prostaglandin F synthase, xylose reductase, rho crystallin, and many others. All possess a similar structure, with a beta-alpha-beta fold characteristic of nucleotide binding proteins.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Aldo Keto Reductase Family 1, Member B15 (AKR1B15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Aldo Keto Reductase Family 1, Member B15 (AKR1B15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aldo Keto Reductase Family 1, Member B15 (AKR1B15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Aldo Keto Reductase Family 1, Member B15 (AKR1B15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Aldo Keto Reductase Family 1, Member B15 (AKR1B15) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Aldo Keto Reductase Family 1, Member B15 (AKR1B15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Aldo Keto Reductase Family 1, Member B15 (AKR1B15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aldo Keto Reductase Family 1, Member B15 (AKR1B15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Aldo Keto Reductase Family 1, Member B15 (AKR1B15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Aldo Keto Reductase Family 1, Member B15 (AKR1B15) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Aldo Keto Reductase Family 1, Member B15 (AKR1B15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Aldo Keto Reductase Family 1, Member B15 (AKR1B15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aldo Keto Reductase Family 1, Member B15 (AKR1B15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Aldo Keto Reductase Family 1, Member B15 (AKR1B15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Aldo Keto Reductase Family 1, Member B15 (AKR1B15) ELISA Kit Customized Service Offer
  1. "Functional expression of novel human and murine AKR1B genes."Chem. Biol. Interact. 191:177-184(2011) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Aldo-keto reductase 1B15 (AKR1B15): a mitochondrial human aldo-keto reductase with activity towards steroids and 3-keto-acyl-coa conjugates."J. Biol. Chem. 290:6531-6545(2015) [PubMed] [Europe PMC] [Abstract]