Butyrophilin Like Protein 7 (BTNL7)

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Ager; Btnl6; Cyp21a1-ps; Ng5; Rnf5; Tnx; Stk19-ps

Butyrophilin Like Protein 7 (BTNL7)
BTNL7, Contains 1 B30.2/SPRY domain. Butyrophilins (BTN) are related to the myelin oligodendrocyte protein (MOG) and belong to the immunoglobulin superfamily of transmembrane molecules. They are expressed primarily on secretory and intestinal epithelium. Butyrophilins are a major protein component of milk fat droplets and are necessary for droplet secretion. Additionally, butyrophilins can regulate T cell activation. An encephalitogenic T cell response to MOG can be either induced or alternatively suppressed as a consequence of immunological cross-reactivity, or "molecular mimicry" with the extracellular IgV-like domain of the milk protein butyrophilin (BTN). In the Dark Agouti rat, active immunization with native BTN triggers an inflammatory response in the CNS characterized by the formation of scattered meningeal and perivascular infiltrates of T cells and macrophages.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Butyrophilin Like Protein 7 (BTNL7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Butyrophilin Like Protein 7 (BTNL7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Butyrophilin Like Protein 7 (BTNL7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Butyrophilin Like Protein 7 (BTNL7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Butyrophilin Like Protein 7 (BTNL7) ELISA Kit Customized Service Offer
  1. , Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
  2. "The genomic sequence and comparative analysis of the rat major histocompatibility complex."Genome Res. 14:631-639(2004) [PubMed] [Europe PMC] [Abstract].
  3. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution." Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract].