![Cathepsin J (CTSJ)](/upload/item/img/Cathepsin-J-(CTSJ)-86860.jpg)
A 1.28 kb full-length cDNA was obtained which contains an open reading frame of 999 nucleotides and encodes a predicted polypeptide of 333 amino acids. The deduced polypeptide exhibits features characteristic of cysteine proteases of the papain type including the highly conserved residues of the catalytic triad, and was hence named cathepsin J. Cathepsin J represents the murine homologue of a previously described rat cathepsin L-related protein. Mature cathepsin J shows 59.3% identity to mouse cathepsin L and contains the characteristic ER(F/W)NIN motif within the propeptide indicating that this protease belongs to the subgroup of cathepsin L-like cysteine proteases. Ctsj was mapped to mouse chromosome 13 in the vicinity of cathepsin L suggesting that cathepsin J may have arisen by gene duplication from cathepsin L or a common ancestral gene.
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Cathepsin J (CTSJ) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Cathepsin J (CTSJ) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Cathepsin J (CTSJ) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Cathepsin J (CTSJ) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Cathepsin J (CTSJ) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Cathepsin J (CTSJ) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Cathepsin J (CTSJ) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Cathepsin J (CTSJ) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Cathepsin J (CTSJ) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Cathepsin J (CTSJ) | ELISA Kit Customized Service Offer |
- "Cathepsin J, a novel murine cysteine protease of the papain family with a placenta-restricted expression."FEBS Lett. 459:299-304(1999) [PubMed] [Europe PMC] [Abstract]
- "Identification and characterization of a dense cluster of placenta-specific cysteine peptidase genes and related genes on mouse chromosome 13."Genomics 79:225-240(2002) [PubMed] [Europe PMC] [Abstract]
- "The transcriptional landscape of the mammalian genome." Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]