Glyoxalase Domain Containing Protein 5 (GLOD5)

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Glyoxalase Domain Containing Protein 5 (GLOD5)
GLOD5 belongs to the glyoxalase I family. Glyoxalase I catalyzes the isomerization of the hemithioacetal between a 2-oxoaldehyde and glutathione to form S-D -lactoylglutathione. The reaction mechanism probably involves a base-mediated proton transfer with an enediolate intermediate.
Glyoxalase I (isomerase) is a member of the vicinal-oxygen-chelate superfamily which also includes as different enzymes as extradiol dioxygenase (oxidative cleavage of C-C bond), fosfomycin resistance protein (nucleophilic substitution), methylmalonyl-CoA epimerase and bleomycin resistance protein (no enzyme, sequestration). These proteins have in common that they share the same βαβββ-fold that provide a metal coordination site.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glyoxalase Domain Containing Protein 5 (GLOD5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glyoxalase Domain Containing Protein 5 (GLOD5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glyoxalase Domain Containing Protein 5 (GLOD5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glyoxalase Domain Containing Protein 5 (GLOD5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glyoxalase Domain Containing Protein 5 (GLOD5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glyoxalase Domain Containing Protein 5 (GLOD5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glyoxalase Domain Containing Protein 5 (GLOD5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glyoxalase Domain Containing Protein 5 (GLOD5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glyoxalase Domain Containing Protein 5 (GLOD5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glyoxalase Domain Containing Protein 5 (GLOD5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glyoxalase Domain Containing Protein 5 (GLOD5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glyoxalase Domain Containing Protein 5 (GLOD5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glyoxalase Domain Containing Protein 5 (GLOD5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glyoxalase Domain Containing Protein 5 (GLOD5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glyoxalase Domain Containing Protein 5 (GLOD5) ELISA Kit Customized Service Offer
  1. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  2. "Crystal structure of the human glyoxalase domain-containing protein 5."Submitted (AUG-2011) to the PDB data bank