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Fibronectin Type III Domain Containing Protein 3 (FNDC3)

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FNDC3A; HUGO; Human gene expressed in odontoblasts

Fibronectin Type III Domain Containing Protein 3 (FNDC3)
CCC S684
HGNC 20296
MGI 1196463
PubMed 18218838
RGD 1304736
UniProt Q9Y2H6
Wiki FNDC3A
Fndc3a is a member of a three-gene family in mice. Fndc3a, which is expressed in several tissues including testis, encodes a novel protein composed of a proline-rich amino-terminus, nine fibronectin type-III domains, and a hydrophobic carboxy-terminus. Immunohistochemical staining indicated that FNDC3A localizes to the acrosome of spermatids, as well as to Leydig cells in the mouse testis. Acrosomal localization of FNDC3A is observed in spermatids between step 2 and step 10 inclusive. In step 12 spermatids, FNDC3A is largely absent from the acrosomal region with immunostaining being localized to vesicular structures located within the cytoplasm of elongate spermatids. Models are presented for the function of FNDC3A in mediating spermatid-Sertoli adhesion during mouse spermatogenesis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Fibronectin Type III Domain Containing Protein 3 (FNDC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Fibronectin Type III Domain Containing Protein 3 (FNDC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Fibronectin Type III Domain Containing Protein 3 (FNDC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Fibronectin Type III Domain Containing Protein 3 (FNDC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fibronectin Type III Domain Containing Protein 3 (FNDC3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Fibronectin Type III Domain Containing Protein 3 (FNDC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Fibronectin Type III Domain Containing Protein 3 (FNDC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Fibronectin Type III Domain Containing Protein 3 (FNDC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Fibronectin Type III Domain Containing Protein 3 (FNDC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fibronectin Type III Domain Containing Protein 3 (FNDC3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Fibronectin Type III Domain Containing Protein 3 (FNDC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Fibronectin Type III Domain Containing Protein 3 (FNDC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Fibronectin Type III Domain Containing Protein 3 (FNDC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Fibronectin Type III Domain Containing Protein 3 (FNDC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fibronectin Type III Domain Containing Protein 3 (FNDC3) ELISA Kit Customized Service Offer
  1. "HUGO (FNDC3A): a new gene overexpressed in human odontoblasts."J. Dent. Res. 87:131-136(2008) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:63-70(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  14. "Solution structure of fibronectin type III domains derived from human KIAA0970 protein."Submitted (JAN-2006) to the PDB data bank