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Leucine Aminopeptidase 3 (LAP3)

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BLH1; GAL6; YCP1; ApsC; PEPC; Peptidase C; Aminopeptidase C; Cysteine proteinase 1, mitochondrial; Bleomycin hydrolase; Homocysteine-thiolactonase

Leucine Aminopeptidase 3 (LAP3)
CCC S645
PubMed 18338745
UniProt Q01532
Human peptidase C, PEPC (E.C.3.4.1.1), exhibits a previously undescribed genetic polymorphism, detectable in red cells or leukocytes by starch gel electrophoresis. A novel enzyme with a specific phenylalanine aminopeptidase activity (ApsC) from Aspergillus niger (CBS 120.49) has been characterized. The derived amino acid sequence is not similar to any previously characterized aminopeptidase sequence but does share similarity with some mammalian acyl-peptide hydrolase sequences. ApsC was found to be most active towards phenylalanine β-naphthylamide (F-βNA) and phenylalanine para-nitroanilide (F-pNA), but it also displayed activity towards other amino acids with aromatic side chains coupled to βNA; other amino acids with nonaromatic side chains coupled to either pNA or βNA were not hydrolyzed or were poorly hydrolyzed. ApsC was not able to hydrolyze N-acetylalanine-pNA, a substrate for acyl-peptide hydrolases.

Organism species: S. cerevisiae (Yeast)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Leucine Aminopeptidase 3 (LAP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Leucine Aminopeptidase 3 (LAP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Leucine Aminopeptidase 3 (LAP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Leucine Aminopeptidase 3 (LAP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leucine Aminopeptidase 3 (LAP3) ELISA Kit Customized Service Offer
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