Schlafen Family Member 14 (SLFN14)
SLFN14 belongs to the Schlafen family. The Schlafen (Slfn) family of genes are differentially regulated during thymocyte maturation and are preferentially expressed in the lymphoid tissues. Ectopic expression of the prototype member Slfn1 early in the T lineage profoundly alters cell growth and development. In these mice, the DP thymocytes fail to complete maturation, and, depending on the transgene dosage, the number of thymocytes is reduced to 1%-30% of normal. Furthermore, expression of the Schlafen family members in fibroblasts and thymoma cells either retards or ablates cell growth. The conceptual protein sequences deduced for each of the family members have no similarity to characterized proteins and must therefore participate in a heretofore unknown regulatory mechanism guiding both cell growth and T cell development.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Schlafen Family Member 14 (SLFN14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Schlafen Family Member 14 (SLFN14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Schlafen Family Member 14 (SLFN14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Schlafen Family Member 14 (SLFN14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Schlafen Family Member 14 (SLFN14) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Schlafen Family Member 14 (SLFN14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Schlafen Family Member 14 (SLFN14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Schlafen Family Member 14 (SLFN14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Schlafen Family Member 14 (SLFN14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Schlafen Family Member 14 (SLFN14) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Schlafen Family Member 14 (SLFN14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Schlafen Family Member 14 (SLFN14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Schlafen Family Member 14 (SLFN14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Schlafen Family Member 14 (SLFN14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Schlafen Family Member 14 (SLFN14) ELISA Kit Customized Service Offer
  1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]