tRNA Methyltransferase 11 Homolog (TRMT11)

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C6orf75; TRM11; tRNA (guanine(10)-N2)-methyltransferase homolog

tRNA Methyltransferase 11 Homolog (TRMT11)
TRMT11, Belongs to the methyltransferase superfamily. Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
A methyltransferase is a type of transferase enzyme that transfers a methyl group from a donor to an acceptor. Methylation often occurs on nucleic bases in DNA or amino acids in protein structures. Methytransferases use a reactive methyl group bound to sulfur in S-adenosyl methionine (SAM) as the methyl donor. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence, an example of epigenetic modification. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant tRNA Methyltransferase 11 Homolog (TRMT11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to tRNA Methyltransferase 11 Homolog (TRMT11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to tRNA Methyltransferase 11 Homolog (TRMT11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for tRNA Methyltransferase 11 Homolog (TRMT11) CLIA Kit Customized Service Offer
n/a ELISA Kit for tRNA Methyltransferase 11 Homolog (TRMT11) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant tRNA Methyltransferase 11 Homolog (TRMT11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to tRNA Methyltransferase 11 Homolog (TRMT11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to tRNA Methyltransferase 11 Homolog (TRMT11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for tRNA Methyltransferase 11 Homolog (TRMT11) CLIA Kit Customized Service Offer
n/a ELISA Kit for tRNA Methyltransferase 11 Homolog (TRMT11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant tRNA Methyltransferase 11 Homolog (TRMT11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to tRNA Methyltransferase 11 Homolog (TRMT11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to tRNA Methyltransferase 11 Homolog (TRMT11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for tRNA Methyltransferase 11 Homolog (TRMT11) CLIA Kit Customized Service Offer
n/a ELISA Kit for tRNA Methyltransferase 11 Homolog (TRMT11) ELISA Kit Customized Service Offer
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  5. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]