Tubulin Tyrosine Ligase Like Protein 12 (TTLL12)

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Tubulin Tyrosine Ligase Like Protein 12 (TTLL12)
TTLL12, which was predicted to modify tubulins, an established target for tumor therapy. TTLL12 is the most poorly characterized member of a recently discovered 14-member family of proteins that catalyze posttranslational modification of tubulins. human TTLL12 is expressed in the proliferating layer of benign prostate. Expression increases during cancer progression to metastasis. It is highly expressed in many metastatic prostate cancer cell lines. It partially colocalizes with vimentin intermediate filaments and cellular structures containing tubulin, including midbodies, centrosomes, intercellular bridges and the mitotic spindle. Downregulation of TTLL12 affects several posttranslational modifications of tubulin.TTLL12 could contribute to tumorigenesis through effects on the cytoskeleton, tubulin modification and chromosome number stability.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tubulin Tyrosine Ligase Like Protein 12 (TTLL12) ELISA Kit Customized Service Offer
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