≡

Pleckstrin Homology Domain Containing Family H, Member 1 (PLEKHH1)

[Edit]

Pleckstrin Homology Domain Containing Family H, Member 1 (PLEKHH1)
CCC S468
HGNC 17733
MGI 2144989
PubMed 20735361
UniProt Q9ULM0
PLEKKH1 contain pleckstrin (PLEK) homology (PH), myth4, and band 4.1 domains. Pleckstrin homology domain (PH domain) is a protein domain of approximately 120 amino acids that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton.
This domain can bind Phosphatidylinositol lipids within biological membranes (such as Phosphatidylinositol (3,4,5)-trisphosphate and phosphatidylinositol (4,5)-bisphosphate), and proteins such as the beta/gamma-subunits of heterotrimeric G proteins, and protein kinase C. Through these interactions, PH domains play a role in recruiting proteins to different membranes, thus targeting them to appropriate cellular compartments or enabling them to interact with other components of the signal transduction pathways.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pleckstrin Homology Domain Containing Family H, Member 1 (PLEKHH1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pleckstrin Homology Domain Containing Family H, Member 1 (PLEKHH1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pleckstrin Homology Domain Containing Family H, Member 1 (PLEKHH1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pleckstrin Homology Domain Containing Family H, Member 1 (PLEKHH1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pleckstrin Homology Domain Containing Family H, Member 1 (PLEKHH1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pleckstrin Homology Domain Containing Family H, Member 1 (PLEKHH1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pleckstrin Homology Domain Containing Family H, Member 1 (PLEKHH1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pleckstrin Homology Domain Containing Family H, Member 1 (PLEKHH1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pleckstrin Homology Domain Containing Family H, Member 1 (PLEKHH1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pleckstrin Homology Domain Containing Family H, Member 1 (PLEKHH1) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]