Cancer/Testis Antigen Family 45, Member A3 (CT45A3)

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CT45.3

Cancer/Testis Antigen Family 45, Member A3 (CT45A3)
By searching for genes upregulated in testis, followed by RT-PCR and genomic sequence analysis, Chen et al. (2005) identified 6 nearly identical copies of the CT45 gene, designated CT45A1 through CT45A6, on chromosome X. The CT45 genes appeared to be products of a recent gene duplication. RT-PCR and EST analysis revealed 3 CT45 transcript variants that differ in their 3-prime ends and represent the accumulated expression of the CT45 genes. All 3 transcripts encode a deduced 189-amino acid protein that shares significant similarity with DDX26B, SAGE, and DDX26. RT-PCR detected high CT45 expression in testis and variable expression in several cell lines. Chen et al. (2005) determined that each CT45 gene contains 5 exons and spans 8 to 9 kb. The first exon is untranslated.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cancer/Testis Antigen Family 45, Member A3 (CT45A3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cancer/Testis Antigen Family 45, Member A3 (CT45A3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cancer/Testis Antigen Family 45, Member A3 (CT45A3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cancer/Testis Antigen Family 45, Member A3 (CT45A3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cancer/Testis Antigen Family 45, Member A3 (CT45A3) ELISA Kit Customized Service Offer
  1. "Identification of cancer/testis-antigen genes by massively parallel signature sequencing."Proc. Natl. Acad. Sci. U.S.A. 102:7940-7945(2005) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]