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Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4)

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SPANX-N4; CT11.9; Cancer/Testis Antigen Family 11, Member 9; Nuclear-associated protein SPAN-Xn4; SPANX family member N4

Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4)
CCC S355
HGNC 33177
MGI 1920559
RGD 1564369
UniProt Q5MJ08
SPANXN4 represents one of several duplicated family members that are located on the X chromosome. This gene family encodes proteins that play a role in spermiogenesis. These proteins represent a specific subgroup of cancer/testis-associated antigens, and they may be candidates for tumor vaccines. This family member belongs to a subgroup of related genes that are present in all primates and rats and mice, and thus, it represents one of the ancestral family members.
SPANXN genes contain 2 exons and a highly conserved 650-bp intron that includes about 400 bp of an endogenous retrovirus long-terminal repeat (ERV-LTR). SPANXN4 encodes a deduced 159-amino acid protein with a bipartite nuclear localization signal.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sperm Protein Associated With The Nucleus, X-Linked Family, Member N4 (SPANXN4) ELISA Kit Customized Service Offer
  1. "The SPANX gene family of cancer/testis-specific antigens: rapid evolution and amplification in African great apes and hominids."Proc. Natl. Acad. Sci. U.S.A. 101:3077-3082(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27."Genome Res. 15:1477-1486(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]