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Sperm Protein Associated With The Nucleus, X-Linked Family, Member N2 (SPANXN2)

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SPANX-N2; CT11.7; Cancer/Testis Antigen Family 11, Member 7; SPANX family member N2; Nuclear-associated protein SPAN-Xn2

Sperm Protein Associated With The Nucleus, X-Linked Family, Member N2 (SPANXN2)
CCC S353
HGNC 33175
UniProt Q5MJ10
By searching for SPANX-like genes in a region of chromosome X showing SPANX gene duplications, Kouprina et al. (2004) identified several SPANXN genes. SPANXN genes contain 2 exons and a highly conserved 650-bp intron that includes about 400 bp of an endogenous retrovirus long-terminal repeat (ERV-LTR).
SPANXN2 encodes a deduced 180-amino acid protein with a putative monopartite nuclear localization signal. RT-PCR detected SPANXN2 in testis and in a melanoma cell line. Within the SPANXN2 peptide sequence, Westbrook et al. (2006) identified a PEST motif and regions rich in glutamic acid and serine.By genomic sequence analysis, Kouprina et al. (2004) mapped the SPANXN2 gene to a tandem SPANXN gene duplication region on chromosome Xq27.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sperm Protein Associated With The Nucleus, X-Linked Family, Member N2 (SPANXN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sperm Protein Associated With The Nucleus, X-Linked Family, Member N2 (SPANXN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sperm Protein Associated With The Nucleus, X-Linked Family, Member N2 (SPANXN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sperm Protein Associated With The Nucleus, X-Linked Family, Member N2 (SPANXN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sperm Protein Associated With The Nucleus, X-Linked Family, Member N2 (SPANXN2) ELISA Kit Customized Service Offer
  1. "The SPANX gene family of cancer/testis-specific antigens: rapid evolution and amplification in African great apes and hominids."Proc. Natl. Acad. Sci. U.S.A. 101:3077-3082(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27."Genome Res. 15:1477-1486(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]