≡

Prosaposin Like Protein 1 (PSAPL1)

[Edit]

Proactivator polypeptide-like 1; Saposin B-Val-like

Prosaposin Like Protein 1 (PSAPL1)
CCC S350
HGNC 33131
MGI 1924193
UniProt Q6NUJ1
PSAPL1 is a 521 secreted protein that contains two saposin A-type domains and four saposin B-type domains. It is suggested that PSAPL1 may activate the lysosomal degradation of sphingolipids. The gene encoding PSAPL1 is located on chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts of all of the human chromosomes. The saposin family includes four structurally related activator proteins, saposin A, B, C and D, that are cleaved from the single precursor protein prosaposin. Prosaposin is synthesized as a protein that is post-translationally modified to a shorter form and then further glycosylated to yield a secretory product. This form subsequently undergoes partial proteolysis to produce saposin A, B, C and D. Each saposin family member acts in conjunction with hydrolase enzymes to facilitate the breakdown of glycosphingolipids within the lysosome.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prosaposin Like Protein 1 (PSAPL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prosaposin Like Protein 1 (PSAPL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prosaposin Like Protein 1 (PSAPL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prosaposin Like Protein 1 (PSAPL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prosaposin Like Protein 1 (PSAPL1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prosaposin Like Protein 1 (PSAPL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prosaposin Like Protein 1 (PSAPL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prosaposin Like Protein 1 (PSAPL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prosaposin Like Protein 1 (PSAPL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prosaposin Like Protein 1 (PSAPL1) ELISA Kit Customized Service Offer
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]