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RNA Binding Motif Protein 12B (RBM12B)

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RNA Binding Motif Protein 12B (RBM12B)
CCC S320
HGNC 32310
MGI 1919647
PubMed 22984568
UniProt Q8IXT5
RBM12B is a 1,001 amino acid protein containing four RRM domains that is encoded by a gene located on human chromosome 8. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Motif Protein 12B (RBM12B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Motif Protein 12B (RBM12B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Motif Protein 12B (RBM12B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Motif Protein 12B (RBM12B) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Motif Protein 12B (RBM12B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Motif Protein 12B (RBM12B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Motif Protein 12B (RBM12B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Motif Protein 12B (RBM12B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Motif Protein 12B (RBM12B) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Motif Protein 12B (RBM12B) ELISA Kit Customized Service Offer
  1. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  2. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  3. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  4. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]