Transmembrane Protein 165 (TMEM165)

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TMPT27; TPARL; TPA Regulated Locus

Transmembrane Protein 165 (TMEM165)
TMEM165, Belongs to the UPF0016 (TC 9.B.26) family.The Clock gene encodes a basic helix-loop-helix (bHLH)-PAS transcription factor that regulates circadian rhythms in mice.
This region contains the complete loci for the Clock and Tpardl (pFT27) genes, as well as the 3' partial locus of the Neuromedin U gene; sequence analysis also suggests the presence of two previously unidentified genes. Finally, a new BAC transgenic line indicates that the genomic region that is sufficient for rescue of the Clock mutant phenotype is no greater than 120 kb and tightly flanks the 3' end of the Clock gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 165 (TMEM165) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 165 (TMEM165) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 165 (TMEM165) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 165 (TMEM165) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 165 (TMEM165) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 165 (TMEM165) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 165 (TMEM165) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 165 (TMEM165) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 165 (TMEM165) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 165 (TMEM165) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 165 (TMEM165) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 165 (TMEM165) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 165 (TMEM165) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 165 (TMEM165) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 165 (TMEM165) ELISA Kit Customized Service Offer
  1. "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning." Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "Impact of disease-causing mutations on TMEM165 subcellular localization, a recently identified protein involved in CDG-II."Hum. Mol. Genet. 22:2914-2928(2013) [PubMed] [Europe PMC] [Abstract]
  7. "Bone dysplasia as a key feature in three patients with a novel congenital disorder of glycosylation (CDG) type II due to a deep intronic splice mutation in TMEM165."JIMD Rep. 8:145-152(2013) [PubMed] [Europe PMC] [Abstract]
  8. "Newly characterized Golgi-localized family of proteins is involved in calcium and pH homeostasis in yeast and human cells."Proc. Natl. Acad. Sci. U.S.A. 110:6859-6864(2013) [PubMed] [Europe PMC] [Abstract]
  9. "TMEM165 deficiency causes a congenital disorder of glycosylation."Am. J. Hum. Genet. 91:15-26(2012) [PubMed] [Europe PMC] [Abstract]