≡

Zinc Finger Protein 580 (ZNF580)

[Edit]

LDL-induced EC protein

Zinc Finger Protein 580 (ZNF580)
CCC S007
HGNC 29473
MGI 1916242
PubMed 21830064
RGD 1306892
UniProt Q9UK33
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression.
The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins.
Zinc finger protein 580 () is a 478 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF580 contains eight C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNAbinding and transcriptional regulation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 580 (ZNF580) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 580 (ZNF580) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 580 (ZNF580) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 580 (ZNF580) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 580 (ZNF580) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 580 (ZNF580) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 580 (ZNF580) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 580 (ZNF580) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 580 (ZNF580) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 580 (ZNF580) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 580 (ZNF580) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 580 (ZNF580) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 580 (ZNF580) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 580 (ZNF580) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 580 (ZNF580) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  4. "Sphingosine-1-phosphate induces human endothelial VEGF and MMP-2 production via transcription factor ZNF580: novel insights into angiogenesis."Biochem. Biophys. Res. Commun. 395:361-366(2010) [PubMed] [Europe PMC] [Abstract]
  5. "ZNF580, a novel C2H2 zinc-finger transcription factor, interacts with the TGF-beta signal molecule Smad2."Cell Biol. Int. 35:1153-1157(2011) [PubMed] [Europe PMC] [Abstract]
  6. "ROS-induced ZNF580 expression: a key role for H2O2/NF-kappaB signaling pathway in vascular endothelial inflammation."Mol. Cell. Biochem. 359:183-191(2012) [PubMed] [Europe PMC] [Abstract]