≡

RAN Binding Protein 10 (RANBP10)

[Edit]

RAN Binding Protein 10 (RANBP10)
CCC R977
HGNC 29285
MGI 1921584
PubMed 18347012
RGD 1311587
UniProt Q6VN20
RanBP10, as a factor that binds beta-tubulin and associates with megakaryocyte microtubules. Unexpectedly, RanBP10 harbors GEF activity toward Ran.
A point mutation in the candidate GEF domain abolishes exchange activity, RanBP10 as a localized cytoplasmic Ran-GEF. RNA interference-mediated loss of RanBP10 in cultured megakaryocytes disrupts microtubule organization. Spatiotemporally restricted generation of cytoplasmic Ran.GTP may influence organization of the specialized microtubules required in thrombopoiesis and that RanBP10 might serve as a molecular link between Ran and noncentrosomal microtubules. RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAN Binding Protein 10 (RANBP10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAN Binding Protein 10 (RANBP10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAN Binding Protein 10 (RANBP10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAN Binding Protein 10 (RANBP10) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAN Binding Protein 10 (RANBP10) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAN Binding Protein 10 (RANBP10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAN Binding Protein 10 (RANBP10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAN Binding Protein 10 (RANBP10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAN Binding Protein 10 (RANBP10) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAN Binding Protein 10 (RANBP10) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAN Binding Protein 10 (RANBP10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAN Binding Protein 10 (RANBP10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAN Binding Protein 10 (RANBP10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAN Binding Protein 10 (RANBP10) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAN Binding Protein 10 (RANBP10) ELISA Kit Customized Service Offer
  1. "A novel MET-interacting protein shares high sequence similarity with RanBPM, but fails to stimulate MET-induced Ras/Erk signaling."Biochem. Biophys. Res. Commun. 313:320-326(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:143-150(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "RanBP10 acts as a novel coactivator for the androgen receptor."Biochem. Biophys. Res. Commun. 368:121-125(2008) [PubMed] [Europe PMC] [Abstract]
  7. "RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules."J. Biol. Chem. 283:14109-14119(2008) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  13. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]