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ATPase Family, AAA Domain Containing Protein 2B (ATAD2B)

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ATPase Family, AAA Domain Containing Protein 2B (ATAD2B)
CCC R968
HGNC 29230
MGI 2444798
PubMed 23711371
UniProt Q9ULI0
Human ATAD2B shows a high degree of similarity to ATAD2. Both contain an AAA domain and a bromodomain with amino acid sequences sharing 97% and 74% identity, respectively. The expression of ATAD2B was studied in the chicken embryo using a polyclonal antibody raised against a recombinant fragment of human ATAD2B.
The expression of ATAD2B was also studied in human tumors. Oncomine and immunohistochemistry reveal ATAD2B expression in glioblastoma and oligodendroglioma; ATAD2B immunostaining was also elevated in human breast carcinoma. In tumors ATAD2B appears to be cytoplasmic or membrane bound, and not nuclear. ATAD2B may play a role in neuronal differentiation and tumor progression.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase Family, AAA Domain Containing Protein 2B (ATAD2B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase Family, AAA Domain Containing Protein 2B (ATAD2B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase Family, AAA Domain Containing Protein 2B (ATAD2B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase Family, AAA Domain Containing Protein 2B (ATAD2B) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase Family, AAA Domain Containing Protein 2B (ATAD2B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase Family, AAA Domain Containing Protein 2B (ATAD2B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase Family, AAA Domain Containing Protein 2B (ATAD2B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase Family, AAA Domain Containing Protein 2B (ATAD2B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase Family, AAA Domain Containing Protein 2B (ATAD2B) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase Family, AAA Domain Containing Protein 2B (ATAD2B) ELISA Kit Customized Service Offer
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
  4. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  8. "Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components."Nat. Cell Biol. 16:281-293(2014) [PubMed] [Europe PMC] [Abstract]
  9. "Solution structure of the bromodomain of human protein KIAA1240."Submitted (OCT-2006) to the PDB data bank
  10. "Histone recognition and large-scale structural analysis of the human bromodomain family."Cell 149:214-231(2012) [PubMed] [Europe PMC] [Abstract]