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Strawberry Notch Homolog 1 (SBNO1)

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MOP3; Sno; Monocyte protein 3

Strawberry Notch Homolog 1 (SBNO1)
CCC R951
HGNC 22973
MGI 2384298
PubMed 20503374
RGD 1310005
UniProt A3KN83
Sbno1 was strongly expressed in the nucleus of the differentiating cortical neurons during the embryonic stages, whereas it exhibited cytoplasmic distribution in the mature neurons in the adult brain. To investigate the role of Sbno1 in neural differentiation, gain and loss of function experiments of Sbno1 was carried out employing the primary culture system of differentiating neuronal cells isolated from E14.5 mouse embryonic cortex. The effect of the Sbno1 RNAi was rescued by co-introduction of zebrafish sbno1. Overexpression of Sbno1 could significantly increase the number of neurons.Sbno1 can promote neuronal differentiation. Immunoprecipitation study confirmed binding between Sbno1 and Su(H) proteins. Sbno1 knockdown upregulated target genes of Notch signal,such as Hes1 and Hes5.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Strawberry Notch Homolog 1 (SBNO1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Strawberry Notch Homolog 1 (SBNO1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Strawberry Notch Homolog 1 (SBNO1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Strawberry Notch Homolog 1 (SBNO1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Strawberry Notch Homolog 1 (SBNO1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Strawberry Notch Homolog 1 (SBNO1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Strawberry Notch Homolog 1 (SBNO1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Strawberry Notch Homolog 1 (SBNO1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Strawberry Notch Homolog 1 (SBNO1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Strawberry Notch Homolog 1 (SBNO1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Strawberry Notch Homolog 1 (SBNO1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Strawberry Notch Homolog 1 (SBNO1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Strawberry Notch Homolog 1 (SBNO1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Strawberry Notch Homolog 1 (SBNO1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Strawberry Notch Homolog 1 (SBNO1) ELISA Kit Customized Service Offer
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "NovelFam3000 -- uncharacterized human protein domains conserved across model organisms."BMC Genomics 7:48-48(2006) [PubMed] [Europe PMC] [Abstract]
  4. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  11. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]