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Family With Sequence Similarity 53, Member B (FAM53B)

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Family With Sequence Similarity 53, Member B (FAM53B)
CCC R909
HGNC 28968
MGI 1925188
PubMed 23958962
RGD 1310799
UniProt Q14153
Smp which is homologous to the human gene. smp was expressed in actively proliferating cells of the CNS throughout embryogenesis. It belongs to a family of vertebrate-specific genes with no characterized biochemical domains. FAM53B bound 14-3-3 chaperones, as well as SKIIP proteins, adaptor proteins connecting DNA-binding proteins to modulators of transcription. smp inactivation with morpholinos led to delayed epiboly and reduced embryonic size. Absence of Smp activity did not induce apoptosis, but resulted in a reduced cell proliferation rate and enlarged blastomeres. Moreover, smp was shown to control the expression of the pluripotency-associated oct4/pou5f1 gene. In addition, the human homolog FAM53B binds to the SKIIP protein, known to modulate the activity of transcriptional regulators implicated in cell proliferation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 53, Member B (FAM53B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 53, Member B (FAM53B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 53, Member B (FAM53B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 53, Member B (FAM53B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 53, Member B (FAM53B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 53, Member B (FAM53B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 53, Member B (FAM53B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 53, Member B (FAM53B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 53, Member B (FAM53B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 53, Member B (FAM53B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 53, Member B (FAM53B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 53, Member B (FAM53B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 53, Member B (FAM53B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 53, Member B (FAM53B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 53, Member B (FAM53B) ELISA Kit Customized Service Offer
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