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Family With Sequence Similarity 76, Member B (FAM76B)

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Family With Sequence Similarity 76, Member B (FAM76B)
CCC R839
HGNC 28492
MGI 1920076
PubMed 12477932
RGD 1311077
UniProt Q5HYJ3
Wiki FAM76B
FAM76B, Belongs to the FAM76 family. FAM76A and FAM76B pair of paralogues. A sequence alignment of these two proteins highlighted their high degree of conservation, except in the region containing the His-repeat. As hypothesized, the paralogue without the His-tract, FAM76A, presented a diffuse nucleoplasmic staining, while the protein with the polyHis segment, FAM76B, accumulated in nuclear speckles. Similar results were obtained for other pairs of paralogous proteins such as DYRK1A/DYRK1B or POU4F2/POU4F3. Thus, these findings further indicate that the His-repeats in these proteins are necessary for their localization to nuclear speckles.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 76, Member B (FAM76B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 76, Member B (FAM76B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 76, Member B (FAM76B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 76, Member B (FAM76B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 76, Member B (FAM76B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 76, Member B (FAM76B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 76, Member B (FAM76B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 76, Member B (FAM76B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 76, Member B (FAM76B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 76, Member B (FAM76B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 76, Member B (FAM76B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 76, Member B (FAM76B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 76, Member B (FAM76B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 76, Member B (FAM76B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 76, Member B (FAM76B) ELISA Kit Customized Service Offer
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