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Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8 most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorderWerner syndrome. The FAM135B gene product has been provisionally designated FAM135B pending further characterization.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Family With Sequence Similarity 135, Member B (FAM135B) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Family With Sequence Similarity 135, Member B (FAM135B) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Family With Sequence Similarity 135, Member B (FAM135B) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Family With Sequence Similarity 135, Member B (FAM135B) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Family With Sequence Similarity 135, Member B (FAM135B) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPR758Mu01 | Recombinant Family With Sequence Similarity 135, Member B (FAM135B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPR758Mu02 | Recombinant Family With Sequence Similarity 135, Member B (FAM135B) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAR758Mu01 | Polyclonal Antibody to Family With Sequence Similarity 135, Member B (FAM135B) | WB; IHC; ICC; IP. |
| PAR758Mu02 | Polyclonal Antibody to Family With Sequence Similarity 135, Member B (FAM135B) | WB; IHC; ICC; IP. | |
| Assay Kits | SER758Mu | ELISA Kit for Family With Sequence Similarity 135, Member B (FAM135B) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Family With Sequence Similarity 135, Member B (FAM135B) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Family With Sequence Similarity 135, Member B (FAM135B) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Family With Sequence Similarity 135, Member B (FAM135B) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Family With Sequence Similarity 135, Member B (FAM135B) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Family With Sequence Similarity 135, Member B (FAM135B) | ELISA Kit Customized Service Offer |
- "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]