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Collagen Type VI Alpha 6 (COL6a6)

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Collagen Type VI Alpha 6 (COL6a6)
CCC R711
HGNC 27023
MGI 2444259
PubMed 18400749
RGD 1309172
UniProt A6NMZ7
The three new genes are COL6A4, COL6A5 and that encode the α4(VI), α5(VI) and α6(VI) chains. In humans, the COL6A4 gene has been disrupted by a chromosome break. Each of the three new collagen chains contain a 336 amino acid triple helix flanked by seven N-terminal von Willebrand factor A-like-domains (VWA-domains) and two (α4 and α6 chains) or three (α5 chain) C-terminal VWA-domains. In humans, mRNA expression of COL6A5 is restricted to a few tissues including lung, testis and colon. In contrast, the COL6A6 gene is expressed in a wide range of fetal and adult tissues including lung, kidney, liver, spleen, thymus, heart and skeletal muscle. Antibodies to the α6(VI) chain stained the extracellular matrix of human skeletal and cardiac muscle, lung and the territorial matrix of articular cartilage.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Collagen Type VI Alpha 6 (COL6a6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Collagen Type VI Alpha 6 (COL6a6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Collagen Type VI Alpha 6 (COL6a6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Collagen Type VI Alpha 6 (COL6a6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Collagen Type VI Alpha 6 (COL6a6) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Collagen Type VI Alpha 6 (COL6a6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Collagen Type VI Alpha 6 (COL6a6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Collagen Type VI Alpha 6 (COL6a6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Collagen Type VI Alpha 6 (COL6a6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Collagen Type VI Alpha 6 (COL6a6) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Collagen Type VI Alpha 6 (COL6a6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Collagen Type VI Alpha 6 (COL6a6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Collagen Type VI Alpha 6 (COL6a6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Collagen Type VI Alpha 6 (COL6a6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Collagen Type VI Alpha 6 (COL6a6) ELISA Kit Customized Service Offer
  1. "Three novel collagen VI chains with high homology to the alpha 3 chain."J. Biol. Chem. 283:10658-10670(2008) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  5. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]