Poly ADP Ribose Polymerase 8 (PARP8)

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pART16; ADP-ribosyltransferase diphtheria toxin-like 16

Poly ADP Ribose Polymerase 8 (PARP8)
PARP8, Contains 1 PARP catalytic domain. Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Poly ADP Ribose Polymerase 8 (PARP8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Poly ADP Ribose Polymerase 8 (PARP8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Poly ADP Ribose Polymerase 8 (PARP8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Poly ADP Ribose Polymerase 8 (PARP8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Poly ADP Ribose Polymerase 8 (PARP8) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Poly ADP Ribose Polymerase 8 (PARP8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Poly ADP Ribose Polymerase 8 (PARP8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Poly ADP Ribose Polymerase 8 (PARP8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Poly ADP Ribose Polymerase 8 (PARP8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Poly ADP Ribose Polymerase 8 (PARP8) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Poly ADP Ribose Polymerase 8 (PARP8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Poly ADP Ribose Polymerase 8 (PARP8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Poly ADP Ribose Polymerase 8 (PARP8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Poly ADP Ribose Polymerase 8 (PARP8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Poly ADP Ribose Polymerase 8 (PARP8) ELISA Kit Customized Service Offer
  1. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Toward a unified nomenclature for mammalian ADP-ribosyltransferases."Trends Biochem. Sci. 35:208-219(2010) [PubMed] [Europe PMC] [Abstract]
  5. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]