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Solute Carrier Family 35, Member F6 (SLC35F6)

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C2orf18; ANT2BP; ANT2-binding protein; Transport and Golgi organization 9 homolog

Solute Carrier Family 35, Member F6 (SLC35F6)
CCC R543
HGNC 26055
MGI 1922169
PubMed 12975309
RGD 1309228
UniProt Q8N357
Wiki C2orf18
C2orf18 is a molecular target for PDAC treatment. Transcriptional and immunohistochemical analysis validated its overexpression in PDAC cells and limited expression in normal adult organs. Knockdown of C2orf18 by small-interfering RNA in PDAC cell lines resulted in induction of apoptosis and suppression of cancer cell growth, suggesting its essential role in maintaining viability of PDAC cells. C2orf18 was localized in the mitochondria and it could interact with adenine nucleotide translocase 2 (ANT2), which is involved in maintenance of the mitochondrial membrane potential and energy homeostasis, and was indicated some roles in apoptosis. These findings implicated that C2orf18, termed ANT2-binding protein (ANT2BP), might serve as a candidate molecular target for pancreatic cancer therapy.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 35, Member F6 (SLC35F6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 35, Member F6 (SLC35F6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 35, Member F6 (SLC35F6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 35, Member F6 (SLC35F6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 35, Member F6 (SLC35F6) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 35, Member F6 (SLC35F6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 35, Member F6 (SLC35F6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 35, Member F6 (SLC35F6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 35, Member F6 (SLC35F6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 35, Member F6 (SLC35F6) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 35, Member F6 (SLC35F6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 35, Member F6 (SLC35F6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 35, Member F6 (SLC35F6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 35, Member F6 (SLC35F6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 35, Member F6 (SLC35F6) ELISA Kit Customized Service Offer
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  8. "Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis."Cancer Sci. 100:457-464(2009) [PubMed] [Europe PMC] [Abstract]
  9. "The proteome of lysosomes."Proteomics 10:4053-4076(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]