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ATP/GTP Binding Protein Like Protein 4 (AGBL4)

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CCP6; Cytosolic Carboxypeptidase 6

ATP/GTP Binding Protein Like Protein 4 (AGBL4)
CCC R508
HGNC 25892
MGI 1918244
UniProt Q5VU57
In brain, Nna1/CCP1, CCP5, and are broadly distributed, whereas CCP2 and 3 exhibit restricted patterns of expression. Nna1/CCP1, CCP2, CCP5, and CCP6 were found to exhibit a cytosolic distribution, with a slight accumulation of CCP5 in the nucleus.
Nna1/CCP1 and CCP2–6 function in the processing of cytosolic proteins such as alpha-tubulin, which is known to be modified by the removal of a C-terminal tyrosine. Analysis of the forms of alpha tubulin in the olfactory bulb of mice lacking Nna1/CCP1 showed the absence of the detyrosinylated form in the mitral cells. Taken together, these results are consistent with a role for Nna1/CCP1 and the related CCPs in the processing of tubulin.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATP/GTP Binding Protein Like Protein 4 (AGBL4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATP/GTP Binding Protein Like Protein 4 (AGBL4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATP/GTP Binding Protein Like Protein 4 (AGBL4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATP/GTP Binding Protein Like Protein 4 (AGBL4) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATP/GTP Binding Protein Like Protein 4 (AGBL4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATP/GTP Binding Protein Like Protein 4 (AGBL4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATP/GTP Binding Protein Like Protein 4 (AGBL4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATP/GTP Binding Protein Like Protein 4 (AGBL4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATP/GTP Binding Protein Like Protein 4 (AGBL4) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATP/GTP Binding Protein Like Protein 4 (AGBL4) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "Functional segregation and emerging role of cilia-related cytosolic carboxypeptidases (CCPs)."FASEB J. 27:424-431(2013) [PubMed] [Europe PMC] [Abstract]