![ATP/GTP Binding Protein Like Protein 4 (AGBL4)](/upload/item/img/ATP-GTP-Binding-Protein-Like-Protein-4-(AGBL4)-85508.jpg)
In brain, Nna1/CCP1, CCP5, and are broadly distributed, whereas CCP2 and 3 exhibit restricted patterns of expression. Nna1/CCP1, CCP2, CCP5, and CCP6 were found to exhibit a cytosolic distribution, with a slight accumulation of CCP5 in the nucleus.
Nna1/CCP1 and CCP2–6 function in the processing of cytosolic proteins such as alpha-tubulin, which is known to be modified by the removal of a C-terminal tyrosine. Analysis of the forms of alpha tubulin in the olfactory bulb of mice lacking Nna1/CCP1 showed the absence of the detyrosinylated form in the mitral cells. Taken together, these results are consistent with a role for Nna1/CCP1 and the related CCPs in the processing of tubulin.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant ATP/GTP Binding Protein Like Protein 4 (AGBL4) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to ATP/GTP Binding Protein Like Protein 4 (AGBL4) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to ATP/GTP Binding Protein Like Protein 4 (AGBL4) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for ATP/GTP Binding Protein Like Protein 4 (AGBL4) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for ATP/GTP Binding Protein Like Protein 4 (AGBL4) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant ATP/GTP Binding Protein Like Protein 4 (AGBL4) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to ATP/GTP Binding Protein Like Protein 4 (AGBL4) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to ATP/GTP Binding Protein Like Protein 4 (AGBL4) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for ATP/GTP Binding Protein Like Protein 4 (AGBL4) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for ATP/GTP Binding Protein Like Protein 4 (AGBL4) | ELISA Kit Customized Service Offer |
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- "Functional segregation and emerging role of cilia-related cytosolic carboxypeptidases (CCPs)."FASEB J. 27:424-431(2013) [PubMed] [Europe PMC] [Abstract]