C-Type Lectin Domain Family 4, Member G (CLEC4G)

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UNQ431; LSECtin

C-Type Lectin Domain Family 4, Member G (CLEC4G)
The LSECtin (CLEC4G) gene is located between the CD23 and DC-SIGN genes with the three genes arranged in the same orientation. LSECtin encodes a protein with a lectin domain followed by a 110-residue stalk region, a transmembrane domain, and a 31-residue cytoplasmic domain. LSECtin has been previously detected on liver and lymph node sinusoidal endothelial cells at the protein and RNA level.
LSECtin functions as an attachment factor for Ebola virus and SARS, but it does not bind HIV or hepatitis C virus. LSECtin exhibits ligand-induced internalization, and its sugar recognition specificity differs from that of DC-SIGN. The presence of LSECtin on myeloid cells should therefore contribute to expanding their antigen-capture and pathogen-recognition capabilities.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C-Type Lectin Domain Family 4, Member G (CLEC4G) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C-Type Lectin Domain Family 4, Member G (CLEC4G) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C-Type Lectin Domain Family 4, Member G (CLEC4G) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C-Type Lectin Domain Family 4, Member G (CLEC4G) CLIA Kit Customized Service Offer
n/a ELISA Kit for C-Type Lectin Domain Family 4, Member G (CLEC4G) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C-Type Lectin Domain Family 4, Member G (CLEC4G) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C-Type Lectin Domain Family 4, Member G (CLEC4G) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C-Type Lectin Domain Family 4, Member G (CLEC4G) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C-Type Lectin Domain Family 4, Member G (CLEC4G) CLIA Kit Customized Service Offer
n/a ELISA Kit for C-Type Lectin Domain Family 4, Member G (CLEC4G) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C-Type Lectin Domain Family 4, Member G (CLEC4G) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C-Type Lectin Domain Family 4, Member G (CLEC4G) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C-Type Lectin Domain Family 4, Member G (CLEC4G) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C-Type Lectin Domain Family 4, Member G (CLEC4G) CLIA Kit Customized Service Offer
n/a ELISA Kit for C-Type Lectin Domain Family 4, Member G (CLEC4G) ELISA Kit Customized Service Offer
  1. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]