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TBC1 Domain Family, Member 10B (TBC1D10B)

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Rab27A-GAP-beta

TBC1 Domain Family, Member 10B (TBC1D10B)
CCC R249
HGNC 24510
MGI 1915699
PubMed 21919203
RGD 1309191
UniProt Q4KMP7
Small G proteins of the RAB family function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family.
The TBC domain is predicted to function as a RabGAP, and the DAYF motif is predicted to interact with PDZ domains. TBC1D10B shares highest sequence similarity with EPI64 (TBC1D10A). The TBC domains of TBC1D10B and TBC1D10A are 81% identical, and both contain a highly conserved catalytic arginine. Fluorescence-tagged TBC1D10B localized to the plasma membrane of transfected mouse melanoma cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TBC1 Domain Family, Member 10B (TBC1D10B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TBC1 Domain Family, Member 10B (TBC1D10B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TBC1 Domain Family, Member 10B (TBC1D10B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TBC1 Domain Family, Member 10B (TBC1D10B) CLIA Kit Customized Service Offer
n/a ELISA Kit for TBC1 Domain Family, Member 10B (TBC1D10B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TBC1 Domain Family, Member 10B (TBC1D10B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TBC1 Domain Family, Member 10B (TBC1D10B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TBC1 Domain Family, Member 10B (TBC1D10B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TBC1 Domain Family, Member 10B (TBC1D10B) CLIA Kit Customized Service Offer
n/a ELISA Kit for TBC1 Domain Family, Member 10B (TBC1D10B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TBC1 Domain Family, Member 10B (TBC1D10B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TBC1 Domain Family, Member 10B (TBC1D10B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TBC1 Domain Family, Member 10B (TBC1D10B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TBC1 Domain Family, Member 10B (TBC1D10B) CLIA Kit Customized Service Offer
n/a ELISA Kit for TBC1 Domain Family, Member 10B (TBC1D10B) ELISA Kit Customized Service Offer
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