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THUMP Domain Containing Protein 1 (THUMPD1)

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THUMP Domain Containing Protein 1 (THUMPD1)
CCC R154
HGNC 23807
MGI 2444479
RGD 1308854
UniProt Q9NXG2
THUMPD1 contains a THUMP domain which is a module of 100-110 amino acid residues which is involved RNA metabolism. The function of this protein has not yet been determined.
The THUMP domain is shared by 4-thiouridine, pseudouridine synthases and RNA methylases and is probably an RNA-binding domain that adopts an alpha/beta fold similar to that found in the C-terminal domain of translation initiation factor 3 and ribosomal protein S8. The THUMP domain probably functions by delivering a variety of RNA modification enzymes to their targets.The existence of a new putative RNA-binding domain, abbreviated THUMP, was deduced from sequence comparison of various proteins known or predicted to be involved in RNA metabolism. For a long time, the THUMP domain remained essentially uncharacterized.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant THUMP Domain Containing Protein 1 (THUMPD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to THUMP Domain Containing Protein 1 (THUMPD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to THUMP Domain Containing Protein 1 (THUMPD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for THUMP Domain Containing Protein 1 (THUMPD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for THUMP Domain Containing Protein 1 (THUMPD1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant THUMP Domain Containing Protein 1 (THUMPD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to THUMP Domain Containing Protein 1 (THUMPD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to THUMP Domain Containing Protein 1 (THUMPD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for THUMP Domain Containing Protein 1 (THUMPD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for THUMP Domain Containing Protein 1 (THUMPD1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant THUMP Domain Containing Protein 1 (THUMPD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to THUMP Domain Containing Protein 1 (THUMPD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to THUMP Domain Containing Protein 1 (THUMPD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for THUMP Domain Containing Protein 1 (THUMPD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for THUMP Domain Containing Protein 1 (THUMPD1) ELISA Kit Customized Service Offer
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  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  13. "Solution structure of the THUMP domain of THUMP domain-containing protein 1."Submitted (SEP-2006) to the PDB data bank