Lipase N (LIPN)

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LIPL4; Lipase-Like, Ab-Hydrolase Domain Containing 4

Lipase N (LIPN)
LIPN belongs to the AB hydrolase superfamily. Lipase family. Exclusively expressed in the epidermis within the granular keratinocytes. Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers.
A lipase is a water-soluble enzyme that catalyzes the hydrolysis of ester chemical bonds in water-insoluble lipid substrates. Lipases are a subclass of the esterases. Lipases perform essential roles in the digestion, transport and processing of dietary lipids in most, if not all, living organisms. Genes encoding lipases are even present in certain viruses. Most lipases act at a specific position on the glycerol backbone of lipid substrate (A1, A2 or A3).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lipase N (LIPN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lipase N (LIPN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lipase N (LIPN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lipase N (LIPN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lipase N (LIPN) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lipase N (LIPN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lipase N (LIPN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lipase N (LIPN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lipase N (LIPN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lipase N (LIPN) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lipase N (LIPN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lipase N (LIPN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lipase N (LIPN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lipase N (LIPN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lipase N (LIPN) ELISA Kit Customized Service Offer
  1. "Large-scale identification of human genes implicated in epidermal barrier function."Genome Biol. 8:R107.1-R107.23(2007) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  3. "A mutation in LIPN, encoding epidermal lipase N, causes a late-onset form of autosomal-recessive congenital ichthyosis."Am. J. Hum. Genet. 88:482-487(2011) [PubMed] [Europe PMC] [Abstract]