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RWD Domain Containing Protein 1 (RWDD1)

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DFRP2; DRG family-regulatory protein 2

RWD Domain Containing Protein 1 (RWDD1)
CCC Q899
HGNC 20993
MGI 1913771
PubMed 18761815
UniProt Q9H446
Rwdd1 is a thymus aging-related protein which contains an RWD domain at its N-terminus. Rwdd1 was expressed in both thymocytes and thymic epithelial cells and located primarily in the cytoplasm. Rwdd1 expression in thymus was decreased in aged and oxidatively stressed mice. This phenomenon was also seen in the Escherichia coli expressed GST-tagged as well as the eukaryotic cell expressed Rwdd1.
Rwdd1 had a similar amino acid composition as Gir2, a member of intrinsically unstructured protein (IUP) family which also showed abnormal electrophoresis behavior. Therefore, biophysical characteristics of Rwdd1 were further illuminated by using approaches such as folding status prediction, mass spectrometry,and proteinase proteolysis. Rwdd1 has the characteristic of a natively unfolded structure.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RWD Domain Containing Protein 1 (RWDD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RWD Domain Containing Protein 1 (RWDD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RWD Domain Containing Protein 1 (RWDD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RWD Domain Containing Protein 1 (RWDD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RWD Domain Containing Protein 1 (RWDD1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RWD Domain Containing Protein 1 (RWDD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RWD Domain Containing Protein 1 (RWDD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RWD Domain Containing Protein 1 (RWDD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RWD Domain Containing Protein 1 (RWDD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RWD Domain Containing Protein 1 (RWDD1) ELISA Kit Customized Service Offer
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  9. "Solution structure of the RWD domain of human RWD domain containing protein 1."Submitted (AUG-2007) to the PDB data bank