TDP Glucose-4,6-Dehydratase (TGDS)
[Edit]TDPGD; SDR2E1; Short Chain Dehydrogenase/Reductase Family 2E, Member 1; dTDP-D-glucose 4,6-dehydratase
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TGDS belongs to the sugar epimerase family. dTDP-glucose dehydratase subfamily. In enzymology, a dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) is an enzyme that catalyzes the chemical reaction: dTDP-glucose<=>dTDP-4-dehydro-6-deoxy-D-glucose + H2O
This enzyme has one substrate, dTDP-glucose, and two products, dTDP-4-dehydro-6-deoxy-D-glucose and H2O.This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. This enzyme participates in 4 metabolic pathways: nucleotide sugars metabolism, streptomycin biosynthesis, polyketide sugar unit biosynthesis, and biosynthesis of vancomycin group antibiotics. It employs one cofactor, NAD+.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant TDP Glucose-4,6-Dehydratase (TGDS) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to TDP Glucose-4,6-Dehydratase (TGDS) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to TDP Glucose-4,6-Dehydratase (TGDS) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for TDP Glucose-4,6-Dehydratase (TGDS) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for TDP Glucose-4,6-Dehydratase (TGDS) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant TDP Glucose-4,6-Dehydratase (TGDS) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to TDP Glucose-4,6-Dehydratase (TGDS) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to TDP Glucose-4,6-Dehydratase (TGDS) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for TDP Glucose-4,6-Dehydratase (TGDS) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for TDP Glucose-4,6-Dehydratase (TGDS) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant TDP Glucose-4,6-Dehydratase (TGDS) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to TDP Glucose-4,6-Dehydratase (TGDS) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to TDP Glucose-4,6-Dehydratase (TGDS) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for TDP Glucose-4,6-Dehydratase (TGDS) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for TDP Glucose-4,6-Dehydratase (TGDS) | ELISA Kit Customized Service Offer |
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- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Homozygous and compound-heterozygous mutations in TGDS cause Catel-Manzke syndrome." Am. J. Hum. Genet. 95:763-770(2014) [PubMed] [Europe PMC] [Abstract]