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Enah/Vasp Like Protein (EVL)

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RNB6; Enabled/Vasodilator Stimulated Phosphoprotein Like protein

Enah/Vasp Like Protein (EVL)
CCC Q820
HGNC 20234
MGI 1194884
PubMed 10945997
RGD 621150
UniProt Q9UI08
Wiki EVL
EVL was found in F-actin-rich patches and at the distal tips of the microspikes that formed on the activated side of the T-cells. Like the other family members, EVL localized to focal adhesions and the leading edge of lamellipodia when expressed in fibroblasts. EVL was a substrate for the cAMP-dependent protein kinase, and this phosphorylation regulated several of the interactions between EVL and its ligands. EVL nucleated actin polymerization under physiological conditions, whereas phosphorylation of both EVL and VASP decreased their nucleating activity. EVL bound directly to the Abl, Lyn, and nSrc SH3 domains; the FE65 WW domain; and profilin, likely via its proline-rich core. Binding of Abl and nSrc SH3 domains, but not profilin or other SH3 domains, was abolished by cAMP-dependent protein kinase phosphorylation of EVL.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ820Hu01 Recombinant Enah/Vasp Like Protein (EVL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAQ820Hu01 Polyclonal Antibody to Enah/Vasp Like Protein (EVL) WB; IHC; ICC; IP.
MAQ820Hu21 Monoclonal Antibody to Enah/Vasp Like Protein (EVL) WB; IHC; ICC; IP.
Assay Kits SEQ820Hu ELISA Kit for Enah/Vasp Like Protein (EVL) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ820Mu01 Recombinant Enah/Vasp Like Protein (EVL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Enah/Vasp Like Protein (EVL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Enah/Vasp Like Protein (EVL) Polyclonal Antibody Customized Service Offer
Assay Kits SEQ820Mu ELISA Kit for Enah/Vasp Like Protein (EVL) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Enah/Vasp Like Protein (EVL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Enah/Vasp Like Protein (EVL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Enah/Vasp Like Protein (EVL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Enah/Vasp Like Protein (EVL) CLIA Kit Customized Service Offer
n/a ELISA Kit for Enah/Vasp Like Protein (EVL) ELISA Kit Customized Service Offer
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