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Asunder Spermatogenesis Regulator (ASUN)

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C12orf11; GCT1; Mat89Bb; NET48; SPATA30; Cell cycle regulator Mat89Bb homolog; Sarcoma antigen NY-SAR-95; Germ cell tumor 1

Asunder Spermatogenesis Regulator (ASUN)
CCC Q813
HGNC 20174
MGI 1918427
PubMed 12414650
RGD 1592236
UniProt Q9NVM9
Wiki C12orf11
C12orf11 belongs to the Cell cycle regulator C12orf11 family. Mat89Bb is separated from Mst89B by at most 100 bp; Mst89B and Mat89Ba are convergently transcribed and their 3' untranslated regions (UTRs) overlap by a minimum of 85 bp.
These sequences, belonging to coding regions of two novel genes designated here as GCT1 and GCT2, were broadly expressed in a panel of human tissues, including testis and ovary. GCT1 and GCT2 were overexpressed in 92 and 71 percent, respectively, of a panel of seminomas tested. Combined array comparative genomic hybridization and array expression analysis is a valid approach for gene discovery in large chromosomal amplicons.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Asunder Spermatogenesis Regulator (ASUN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Asunder Spermatogenesis Regulator (ASUN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Asunder Spermatogenesis Regulator (ASUN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Asunder Spermatogenesis Regulator (ASUN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Asunder Spermatogenesis Regulator (ASUN) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Asunder Spermatogenesis Regulator (ASUN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Asunder Spermatogenesis Regulator (ASUN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Asunder Spermatogenesis Regulator (ASUN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Asunder Spermatogenesis Regulator (ASUN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Asunder Spermatogenesis Regulator (ASUN) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Asunder Spermatogenesis Regulator (ASUN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Asunder Spermatogenesis Regulator (ASUN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Asunder Spermatogenesis Regulator (ASUN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Asunder Spermatogenesis Regulator (ASUN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Asunder Spermatogenesis Regulator (ASUN) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Immunomic analysis of human sarcoma."Proc. Natl. Acad. Sci. U.S.A. 100:2651-2656(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Genomic and expression analysis of the 12p11-p12 amplicon using EST arrays identifies two novel amplified and overexpressed genes."Cancer Res. 62:6218-6223(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Drosophila genome-scale screen for PAN GU kinase substrates identifies Mat89Bb as a cell cycle regulator."Dev. Cell 8:435-442(2005) [PubMed] [Europe PMC] [Abstract]
  8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  13. "Human Asunder promotes dynein recruitment and centrosomal tethering to the nucleus at mitotic entry."Mol. Biol. Cell 23:4713-4724(2012) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  15. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]