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Ubiquitin Specific Peptidase 41 (USP41)

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Putative ubiquitin carboxyl-terminal hydrolase 41; Deubiquitinating enzyme 41; Ubiquitin thioesterase 41; Ubiquitin-specific-processing protease 41

Ubiquitin Specific Peptidase 41 (USP41)
CCC Q800
HGNC 20070
UniProt Q3LFD5
The C19 family of ubiquitin specific proteases (USPs) deserves a particular analysis due to its large size and extreme complexity.The catalog of rat USPs includes Usp4, Usp18, and Usp19 absent in the current genome assembly but experimentally verified, as well as Usp9y—the only protease gene reported to date in chromosome Y—the sequence of which is not yet available in rat. Analysis of rat USPs shows some interesting differences with their human and mouse counterparts. USP41 is also absent in rat and mouse but present in the human lineage.
USP41 belongs to the peptidase C19 family. May recognize and hydrolyze the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly- ubiquitin precursors as well as that of ubiquinated proteins.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ubiquitin Specific Peptidase 41 (USP41) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ubiquitin Specific Peptidase 41 (USP41) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ubiquitin Specific Peptidase 41 (USP41) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ubiquitin Specific Peptidase 41 (USP41) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Specific Peptidase 41 (USP41) ELISA Kit Customized Service Offer
  1. "The DNA sequence of human chromosome 22." Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases."Biochem. Biophys. Res. Commun. 314:54-62(2004) [PubMed] [Europe PMC] [Abstract]