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FERM Domain Containing Protein 6 (FRMD6)

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EX1; C14orf31; Willin

FERM Domain Containing Protein 6 (FRMD6)
CCC Q780
HGNC 19839
MGI 2442579
PubMed 21666719
RGD 727810
UniProt Q96NE9
Wiki FRMD6
FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. is a 622 amino acid cytoplasmic and peripheral membrane protein that can co-localize with Actin and exists as three alternatively spliced isoforms. Containing one FERM domain within its N-terminus, FRMD6 binds phospholipids and is encoded by a gene mapping to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer’s disease (AD).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant FERM Domain Containing Protein 6 (FRMD6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to FERM Domain Containing Protein 6 (FRMD6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to FERM Domain Containing Protein 6 (FRMD6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for FERM Domain Containing Protein 6 (FRMD6) CLIA Kit Customized Service Offer
n/a ELISA Kit for FERM Domain Containing Protein 6 (FRMD6) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant FERM Domain Containing Protein 6 (FRMD6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to FERM Domain Containing Protein 6 (FRMD6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to FERM Domain Containing Protein 6 (FRMD6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for FERM Domain Containing Protein 6 (FRMD6) CLIA Kit Customized Service Offer
n/a ELISA Kit for FERM Domain Containing Protein 6 (FRMD6) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant FERM Domain Containing Protein 6 (FRMD6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to FERM Domain Containing Protein 6 (FRMD6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to FERM Domain Containing Protein 6 (FRMD6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for FERM Domain Containing Protein 6 (FRMD6) CLIA Kit Customized Service Offer
n/a ELISA Kit for FERM Domain Containing Protein 6 (FRMD6) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A novel 4.1 ezrin radixin moesin (FERM)-containing protein, 'Willin'."FEBS Lett. 579:5089-5094(2005) [PubMed] [Europe PMC] [Abstract]
  6. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]