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C5orf12 is a putative membrane protein belonging to the TMS_TDE family. The cDNA encodes 423 amino acid with a putative molecular weight of about 47 KDa.
Secondary structure prediction showed that C5orf12 contained 10 putative transmembrane helices, which has high identity with other family members. C5orf12 was highly expressed in placenta, skeletal muscle, spleen, thymus, testis and peripheral leukocyte while expressed weakly in heart and liver. C5orf12 has high identity with the rat TPO1, C5orf12 may also have a role in the brain development. Myelin throughout the brain is enriched with Serinc5, which was down-regulated in the hippocampus by seizures.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Serine Incorporator 5 (SERINC5) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Serine Incorporator 5 (SERINC5) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Serine Incorporator 5 (SERINC5) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Serine Incorporator 5 (SERINC5) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Serine Incorporator 5 (SERINC5) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Serine Incorporator 5 (SERINC5) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Serine Incorporator 5 (SERINC5) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Serine Incorporator 5 (SERINC5) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Serine Incorporator 5 (SERINC5) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Serine Incorporator 5 (SERINC5) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Serine Incorporator 5 (SERINC5) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Serine Incorporator 5 (SERINC5) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Serine Incorporator 5 (SERINC5) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Serine Incorporator 5 (SERINC5) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Serine Incorporator 5 (SERINC5) | ELISA Kit Customized Service Offer |
- "Cloning and expression of a novel human C5orf12 gene, a member of the TMS_TDE family."Mol. Biol. Rep. 30:47-52(2003) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]