Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3)
[Edit]HELIC1; RNAH; ASC1p200; RNA Helicase Family; Helicase, ATP Binding 1; Trip4 complex subunit p200; ASC-1 complex subunit p200
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ASCC3 belongs to the helicase family. Enhances NF-kappa-B, SRF and AP1 transactivation.ASC-1 harbors an autonomous transactivation domain that contains a putative zinc finger motif which provides binding sites for basal transcription factors TBP and TFIIA,SRC-1 and CBP-p300, and nuclear receptors, as demonstrated by the glutathione S-transferase pull-down assays and the yeast two-hybrid tests. The ASC-1 binding sites involve the hinge domain but not the C-terminal AF2 core domain of nuclear receptors. Nonetheless, ASC-1 appears to require the AF2-dependent factors to function, as suggested by the ability of ASC-1 to coactivate nuclear receptors, either alone or in cooperation with SRC-1 and p300, as well as its inability to coactivate a mutant receptor lacking the AF2 core domain.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPQ709Hu01 | Recombinant Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAQ709Hu01 | Polyclonal Antibody to Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | WB; IHC; ICC; IP. |
MAQ709Hu21 | Monoclonal Antibody to Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | WB; IHC; ICC; IP. | |
Assay Kits | SEQ709Hu | ELISA Kit for Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) | ELISA Kit Customized Service Offer |
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