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RNA Binding Region Containing Protein 3 (RNPC3)

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RBM40; RNP; U11/U12 snRNP 65K; RNA-binding protein 40; RNA-binding region-containing protein 3; U11/U12 small nuclear ribonucleoprotein 65 kDa protein

RNA Binding Region Containing Protein 3 (RNPC3)
CCC Q707
HGNC 18666
MGI 1914475
RGD 1582776
UniProt Q96LT9
Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. RNPC3 encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.Highly expressed in pancreas and kidney. Detected at lower levels in heart, brain, placenta, lung, liver, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Region Containing Protein 3 (RNPC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Region Containing Protein 3 (RNPC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Region Containing Protein 3 (RNPC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Region Containing Protein 3 (RNPC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Region Containing Protein 3 (RNPC3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Region Containing Protein 3 (RNPC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Region Containing Protein 3 (RNPC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Region Containing Protein 3 (RNPC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Region Containing Protein 3 (RNPC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Region Containing Protein 3 (RNPC3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Region Containing Protein 3 (RNPC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Region Containing Protein 3 (RNPC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Region Containing Protein 3 (RNPC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Region Containing Protein 3 (RNPC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Region Containing Protein 3 (RNPC3) ELISA Kit Customized Service Offer
  1. "Cloning and identification of a novel human RNPC3 gene that encodes a protein with two RRM domains and is expressed in the cell nucleus."Biochem. Genet. 41:315-323(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome."RNA 10:929-941(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 8:85-95(2001) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  8. "The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K protein."EMBO J. 24:3057-3069(2005) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  11. "Functional stabilization of an RNA recognition motif by a noncanonical N-terminal expansion."RNA 15:1305-1313(2009) [PubMed] [Europe PMC] [Abstract]