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Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2)

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C9orf99; SDR13C1; Short Chain Dehydrogenase/Reductase Family 13C, Member 1

Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2)
CCC Q698
HGNC 18572
MGI 1919729
RGD 1305387
UniProt Q6YN16
Hydroxysteroid dehydrogenases (HSDs) are responsible for the biosynthesis of steroid hormones and play a crucial role in mammalian physiology and development.
HSDL2 is 3211 bp in length, encoding a 418-amino-acid polypeptide, which contains a typical motif for NAD(P)+-binding (TGxxxGxG), an SDR active site motif (S-Y-K) and a sterol carrier protein domain. HSDL2 shows high similarity with the homologues in the mouse and fruit fly. The HSDL2 gene is mapped to chromosome 9q32 and contains 11 exons. RT-PCR analysis shows that the HSDL2 gene is widely expressed in human tissues and the expression levels in liver, kidney, prostate, testis, and ovary are relatively high.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hydroxysteroid Dehydrogenase Like Protein 2 (HSDL2) ELISA Kit Customized Service Offer
  1. "Molecular cloning and characterization of a novel human hydroxysteroid dehydrogenase-like 2 (HSDL2) cDNA from fetal brain."Biochem. Genet. 41:165-174(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "In search for function of two human orphan SDR enzymes: Hydroxysteroid dehydrogenase like 2 (HSDL2) and short-chain dehydrogenase/reductase-orphan (SDR-O)."J. Steroid Biochem. Mol. Biol. 117:117-124(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  9. "Crystal structure of the catalytic domain of human hydroxysteroid dehydrogenase like 2 (HSDL2)."Submitted (MAR-2010) to the PDB data bank