Peroxisomal Testis Specific Protein 1 (PXT1)

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STEPP; Small testis-specific peroxisomal protein

Peroxisomal Testis Specific Protein 1 (PXT1)
Genes reported to be crucial for spermatogenesis are often exclusively expressed in the testis. The putative amino acid sequence encoded by the cDNA of the Pxt1 gene contains a conserved Asn-His-Leu (NHL)-motif at its C-terminal end, which is characteristic for peroxisomal proteins. Pxt1-EGFP fusion protein is co-localized with known peroxisomal marker proteins in transfected NIH3T3 cells. The peroxisomal targeting signal NHL is functional and responsible for the correct subcellular localization of the Pxt1-EGFP fusion protein. In male germ cells peroxisomes were reported only in spermatogonia. The Pxt1 gene is so far the first gene coding for a putative peroxisomal protein which is expressed in later steps of spermatogenesis, namely in pachytene spermatocytes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Peroxisomal Testis Specific Protein 1 (PXT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Peroxisomal Testis Specific Protein 1 (PXT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Peroxisomal Testis Specific Protein 1 (PXT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Peroxisomal Testis Specific Protein 1 (PXT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Peroxisomal Testis Specific Protein 1 (PXT1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Peroxisomal Testis Specific Protein 1 (PXT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Peroxisomal Testis Specific Protein 1 (PXT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Peroxisomal Testis Specific Protein 1 (PXT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Peroxisomal Testis Specific Protein 1 (PXT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Peroxisomal Testis Specific Protein 1 (PXT1) ELISA Kit Customized Service Offer
  1. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The putative peroxisomal gene Pxt1 is exclusively expressed in the testis."Cytogenet. Genome Res. 119:74-82(2007) [PubMed] [Europe PMC] [Abstract]