CD99 Molecule Like Protein 2 (CD99L2)
[Edit]MIC2L1; CD99B; CD99 Antigen-Like 2; MIC2-like protein 1
CD99L2 encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants.
In contrast to these in vitro results, blocking CD99 or CD99L2 or gene disruption of PECAM-1 trapped neutrophils in vivo between endothelial cells and the underlying basement membrane as revealed by electron microscopy and by 3-dimensional confocal fluorescence microscopy in the inflamed cremaster tissue. Leukocyte extravasation was inhibited in interleukin-1β-inflamed peritoneum and in the cremaster by PECAM-1 gene disruption and was further attenuated by blocking antibodies against CD99 and CD99L2.
In contrast to these in vitro results, blocking CD99 or CD99L2 or gene disruption of PECAM-1 trapped neutrophils in vivo between endothelial cells and the underlying basement membrane as revealed by electron microscopy and by 3-dimensional confocal fluorescence microscopy in the inflamed cremaster tissue. Leukocyte extravasation was inhibited in interleukin-1β-inflamed peritoneum and in the cremaster by PECAM-1 gene disruption and was further attenuated by blocking antibodies against CD99 and CD99L2.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant CD99 Molecule Like Protein 2 (CD99L2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to CD99 Molecule Like Protein 2 (CD99L2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to CD99 Molecule Like Protein 2 (CD99L2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for CD99 Molecule Like Protein 2 (CD99L2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for CD99 Molecule Like Protein 2 (CD99L2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant CD99 Molecule Like Protein 2 (CD99L2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to CD99 Molecule Like Protein 2 (CD99L2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to CD99 Molecule Like Protein 2 (CD99L2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for CD99 Molecule Like Protein 2 (CD99L2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for CD99 Molecule Like Protein 2 (CD99L2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant CD99 Molecule Like Protein 2 (CD99L2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to CD99 Molecule Like Protein 2 (CD99L2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to CD99 Molecule Like Protein 2 (CD99L2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for CD99 Molecule Like Protein 2 (CD99L2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for CD99 Molecule Like Protein 2 (CD99L2) | ELISA Kit Customized Service Offer |
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