CD99 Molecule Like Protein 2 (CD99L2)

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MIC2L1; CD99B; CD99 Antigen-Like 2; MIC2-like protein 1

CD99 Molecule Like Protein 2 (CD99L2)
CD99L2 encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants.
In contrast to these in vitro results, blocking CD99 or CD99L2 or gene disruption of PECAM-1 trapped neutrophils in vivo between endothelial cells and the underlying basement membrane as revealed by electron microscopy and by 3-dimensional confocal fluorescence microscopy in the inflamed cremaster tissue. Leukocyte extravasation was inhibited in interleukin-1β-inflamed peritoneum and in the cremaster by PECAM-1 gene disruption and was further attenuated by blocking antibodies against CD99 and CD99L2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CD99 Molecule Like Protein 2 (CD99L2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CD99 Molecule Like Protein 2 (CD99L2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CD99 Molecule Like Protein 2 (CD99L2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CD99 Molecule Like Protein 2 (CD99L2) CLIA Kit Customized Service Offer
n/a ELISA Kit for CD99 Molecule Like Protein 2 (CD99L2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CD99 Molecule Like Protein 2 (CD99L2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CD99 Molecule Like Protein 2 (CD99L2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CD99 Molecule Like Protein 2 (CD99L2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CD99 Molecule Like Protein 2 (CD99L2) CLIA Kit Customized Service Offer
n/a ELISA Kit for CD99 Molecule Like Protein 2 (CD99L2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CD99 Molecule Like Protein 2 (CD99L2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CD99 Molecule Like Protein 2 (CD99L2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CD99 Molecule Like Protein 2 (CD99L2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CD99 Molecule Like Protein 2 (CD99L2) CLIA Kit Customized Service Offer
n/a ELISA Kit for CD99 Molecule Like Protein 2 (CD99L2) ELISA Kit Customized Service Offer
  1. "Cloning, genomic organization, alternative transcripts and expression analysis of CD99L2, a novel paralog of human CD99, and identification of evolutionary conserved motifs."Gene 307:63-76(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]