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BMP2 Inducible Kinase (BMP2K)

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BIKe

BMP2 Inducible Kinase (BMP2K)
CCC Q642
HGNC 18041
MGI 2155456
PubMed 19927351
UniProt Q9NSY1
Wiki BMP2K
BMP2Kis the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene.
BMP2K gene 1379 G/A variant is strongly correlated with high myopia and may contribute to a genetic risk factor for high degrees of myopic pathogenesis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant BMP2 Inducible Kinase (BMP2K) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to BMP2 Inducible Kinase (BMP2K) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to BMP2 Inducible Kinase (BMP2K) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for BMP2 Inducible Kinase (BMP2K) CLIA Kit Customized Service Offer
n/a ELISA Kit for BMP2 Inducible Kinase (BMP2K) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant BMP2 Inducible Kinase (BMP2K) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to BMP2 Inducible Kinase (BMP2K) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to BMP2 Inducible Kinase (BMP2K) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for BMP2 Inducible Kinase (BMP2K) CLIA Kit Customized Service Offer
n/a ELISA Kit for BMP2 Inducible Kinase (BMP2K) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Selection system for genes encoding nuclear-targeted proteins."Nat. Biotechnol. 16:1338-1342(1998) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  14. "Patterns of somatic mutation in human cancer genomes." Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]