Transmembrane Protein 11 (TMEM11)
[Edit]C17orf35; PMI; PM1; Transmembrane protein 11, mitochondrial
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A transmembrane protein is a polytopic protein that spans the entire biological membrane. Transmembrane proteins aggregate and precipitate in water. They require detergents or nonpolar solvents for extraction, although some of them (beta-barrels) can be also extracted using denaturing agents.
RASSF1A, encodes a pro-apoptotic tumour suppressor and its loss is associated with many cancers including MM. At least two more genes from the same area, TUSC2 and TMEM11, may also be associated with cancer. Forced expression of TUSC2 resulted in tumour growth suppression. It was found that expression of TUSC2 could stimulates p53-regulated apoptosis, and thus both genes might be important TSGs.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Transmembrane Protein 11 (TMEM11) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Transmembrane Protein 11 (TMEM11) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Transmembrane Protein 11 (TMEM11) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Transmembrane Protein 11 (TMEM11) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transmembrane Protein 11 (TMEM11) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Transmembrane Protein 11 (TMEM11) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Transmembrane Protein 11 (TMEM11) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Transmembrane Protein 11 (TMEM11) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Transmembrane Protein 11 (TMEM11) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transmembrane Protein 11 (TMEM11) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Transmembrane Protein 11 (TMEM11) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Transmembrane Protein 11 (TMEM11) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Transmembrane Protein 11 (TMEM11) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Transmembrane Protein 11 (TMEM11) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transmembrane Protein 11 (TMEM11) | ELISA Kit Customized Service Offer |
- "Nucleotide sequence of a cDNA encoding a protein with primary structural similarity to G-protein coupled receptors."Nucleic Acids Res. 18:1896-1896(1990) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "Inner-membrane proteins PMI/TMEM11 regulate mitochondrial morphogenesis independently of the DRP1/MFN fission/fusion pathways."EMBO Rep. 12:223-230(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]