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Ubiquitin Protein Ligase E3C (UBE3C)

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HectH2

Ubiquitin Protein Ligase E3C (UBE3C)
CCC Q559
HGNC 16803
MGI 2140998
PubMed 24158444
RGD 1559986
UniProt Q15386
Wiki UBE3C
UBE3C is a ‘homologous to E6AP C-terminus’ family member involved in substrate protein selection for ubiquitin ligation. Aspirin-intolerant asthma (AIA), as an asthma phenotype that involves the upper or lower airways, occurs from excessive leukotriene production on administration of nonsteroidal anti-inflammatory drugs. The UBE3C gene on chromosome 7 is a member of the E3 ligase enzymes and is implicated in the ubiquitin-proteasome pathway. This pathway is involved in immune responses to inflammation, including asthma.The rs3802122 and rs6979947 polymorphisms were significantly associated with the risk of AIA. However, further studies are required to establish the underlying mechanism by which UBE3C and its polymorphisms affect the risk of AIA.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ubiquitin Protein Ligase E3C (UBE3C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ubiquitin Protein Ligase E3C (UBE3C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ubiquitin Protein Ligase E3C (UBE3C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ubiquitin Protein Ligase E3C (UBE3C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Protein Ligase E3C (UBE3C) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ubiquitin Protein Ligase E3C (UBE3C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ubiquitin Protein Ligase E3C (UBE3C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ubiquitin Protein Ligase E3C (UBE3C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ubiquitin Protein Ligase E3C (UBE3C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Protein Ligase E3C (UBE3C) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ubiquitin Protein Ligase E3C (UBE3C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ubiquitin Protein Ligase E3C (UBE3C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ubiquitin Protein Ligase E3C (UBE3C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ubiquitin Protein Ligase E3C (UBE3C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Protein Ligase E3C (UBE3C) ELISA Kit Customized Service Offer
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  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]