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COMM Domain Containing Protein 7 (COMMD7)

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C20orf92

COMM Domain Containing Protein 7 (COMMD7)
CCC Q517
HGNC 16223
MGI 1914197
PubMed 23049798
RGD 1307786
UniProt Q86VX2
COMMD7 is expressed at high level, 3.1 times the average gene in this release. COMMD7 contains 16 different introns. Transcription produces 10 alternatively spliced mRNAs. There are 2 probable alternative promotors, 2 non overlapping alternative last exons and 3 validated alternative polyadenylation sites . The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of 5 cassette exons, overlapping exons with different boundaries, alternative splicing or retention of 3 introns.
There are 2 articles specifically referring to this gene in PubMed. Proteins are expected to localize in various compartments (cytoplasm, mitochondrion). This gene's in vivo function is yet unknown.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant COMM Domain Containing Protein 7 (COMMD7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to COMM Domain Containing Protein 7 (COMMD7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to COMM Domain Containing Protein 7 (COMMD7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for COMM Domain Containing Protein 7 (COMMD7) CLIA Kit Customized Service Offer
n/a ELISA Kit for COMM Domain Containing Protein 7 (COMMD7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant COMM Domain Containing Protein 7 (COMMD7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to COMM Domain Containing Protein 7 (COMMD7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to COMM Domain Containing Protein 7 (COMMD7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for COMM Domain Containing Protein 7 (COMMD7) CLIA Kit Customized Service Offer
n/a ELISA Kit for COMM Domain Containing Protein 7 (COMMD7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant COMM Domain Containing Protein 7 (COMMD7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to COMM Domain Containing Protein 7 (COMMD7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to COMM Domain Containing Protein 7 (COMMD7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for COMM Domain Containing Protein 7 (COMMD7) CLIA Kit Customized Service Offer
n/a ELISA Kit for COMM Domain Containing Protein 7 (COMMD7) ELISA Kit Customized Service Offer
  1. "COMMD proteins, a novel family of structural and functional homologs of MURR1."J. Biol. Chem. 280:22222-22232(2005) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding."J. Biol. Chem. 286:32355-32365(2011) [PubMed] [Europe PMC] [Abstract]
  7. "Functional interaction of COMMD3 and COMMD9 with the epithelial sodium channel."Am. J. Physiol. 305:F80-F89(2013) [PubMed] [Europe PMC] [Abstract]
  8. "CCDC22 deficiency in humans blunts activation of proinflammatory NF-kappaB signaling."J. Clin. Invest. 123:2244-2256(2013) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  10. "COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A." Mol. Biol. Cell 26:91-103(2015) [PubMed] [Europe PMC] [Abstract]