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Actin Related Protein 5 (ACTR5)

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ARP5; INO80M; INO80 Complex Subunit M; Sarcoma antigen NY-SAR-16

Actin Related Protein 5 (ACTR5)
CCC Q436
HGNC 14671
MGI 1924748
PubMed 19557832
RGD 1307958
UniProt Q9H9F9
ACTR5 belongs to the actin family. ARP5 subfamily.May be involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Component of the chromatin remodeling INO80 complex, at least composed of ACTL6A, ACTR5, ACTR8, RVBL1, RVBL2, INO80, INO80B, INO80C, INO80D and INO80E. The mammalian Tip49a and Tip49b proteins belong to an evolutionarily conserved family of AAA+ ATPases. In Saccharomyces cerevisiae, orthologs of Tip49a and Tip49b, called Rvb1 and Rvb2, respectively, are subunits of two distinct ATP-dependent chromatin remodeling complexes, SWR1 and INO80. similar to the yeast INO80 complex, the hINO80 complex exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Actin Related Protein 5 (ACTR5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Actin Related Protein 5 (ACTR5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Actin Related Protein 5 (ACTR5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Actin Related Protein 5 (ACTR5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Related Protein 5 (ACTR5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Actin Related Protein 5 (ACTR5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Actin Related Protein 5 (ACTR5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Actin Related Protein 5 (ACTR5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Actin Related Protein 5 (ACTR5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Related Protein 5 (ACTR5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Actin Related Protein 5 (ACTR5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Actin Related Protein 5 (ACTR5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Actin Related Protein 5 (ACTR5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Actin Related Protein 5 (ACTR5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Related Protein 5 (ACTR5) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Immunomic analysis of human sarcoma."Proc. Natl. Acad. Sci. U.S.A. 100:2651-2656(2003) [PubMed] [Europe PMC] [Abstract]
  5. "A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex."J. Biol. Chem. 280:41207-41212(2005) [PubMed] [Europe PMC] [Abstract]
  6. "A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair."Nat. Struct. Mol. Biol. 14:1165-1172(2007) [PubMed] [Europe PMC] [Abstract]
  7. "The actin-related protein hArp8 accumulates on the mitotic chromosomes and functions in chromosome alignment."Exp. Cell Res. 314:859-868(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex."Mol. Cell 31:909-917(2008) [PubMed] [Europe PMC] [Abstract]
  9. "The human actin-related protein hArp5: nucleo-cytoplasmic shuttling and involvement in DNA repair."Exp. Cell Res. 315:206-217(2009) [PubMed] [Europe PMC] [Abstract]
  10. "INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway."Proc. Natl. Acad. Sci. U.S.A. 107:17274-17279(2010) [PubMed] [Europe PMC] [Abstract]
  11. "Subunit organization of the human INO80 chromatin remodeling complex: An evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling."J. Biol. Chem. 286:11283-11289(2011) [PubMed] [Europe PMC] [Abstract]