≡

Bobby Sox Homolog (BBX)

[Edit]

HBP2; HMG box-containing protein 2; HMG box transcription factor BBX

Bobby Sox Homolog (BBX)
CCC Q423
HGNC 14422
MGI 1917758
PubMed 21677718
RGD 1309769
UniProt Q8WY36
Wiki BBX
HBP2, a new mammalian protein that complements the fission yeast MBF transcription complex. The mammalian HBP2 gene has been isolated by functional complementation of cells unable to undergo DNA replication in fission yeast. HBP2 is a protein with a high mobility group (HMG) domain that belongs to the Sox (Sry-related HMG box) family of transcription factors. As in other members of the family, the HMG box in HBP2 is a DNA-binding domain that is essential for its function in Schizosaccharomyces pombe. Expression of HBP2 in fission yeast activates CdclO-dependent transcription at G1/S and allows growth of cdc10-129, resldelta and rep2delta mutant cells at the restrictive temperature. The mammalian HBP2 activates transcription at G1/S in the fission yeast Sch. pombe.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bobby Sox Homolog (BBX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bobby Sox Homolog (BBX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bobby Sox Homolog (BBX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bobby Sox Homolog (BBX) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bobby Sox Homolog (BBX) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bobby Sox Homolog (BBX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bobby Sox Homolog (BBX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bobby Sox Homolog (BBX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bobby Sox Homolog (BBX) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bobby Sox Homolog (BBX) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bobby Sox Homolog (BBX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bobby Sox Homolog (BBX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bobby Sox Homolog (BBX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bobby Sox Homolog (BBX) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bobby Sox Homolog (BBX) ELISA Kit Customized Service Offer
  1. "HBP2: a new mammalian protein that complements the fission yeast MBF transcription complex."Curr. Genet. 40:110-118(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]